OPERA
Optimal Pregnancy Environment Risk Assessment


OPERA is an international, interdisciplinary program of women’s health researchers, care providers, foundations and international agencies dedicated to discovering and disseminating inexpensive and accessible tools to diagnose those women at risk for preterm birth (PTB) or other adverse pregnancy outcome as early as possible in pregnancy and to promoting effective interventions to mitigate these risks. OPERA’s initial efforts will focus on risk diagnosis in populations of vulnerable women in any jurisdiction. OPERA receives support from the Worldwide Universities Network (WUN) and is recognized by the World Health Organization (WHO). OPERA promotes prediction projects in local jurisdictions and connects teams and jurisdictions via a website and meetings.

OPERA intends to build a sustainable international organization that will provide guidance and support for studies of cohorts of pregnant women in order to develop evidence to 1) determine how to assess risk for preterm birth and other adverse pregnancy outcomes simply, inexpensively and as early as possible in pregnancy, 2) to identify the women in the highest (20%) at-risk group (with 80% precision), and 3) to share this information with other studies, care-providers and interested parties. OPERA is not a funding organization but instead provides support in terms of special skills, study design, data evaluation and sharing, guidance, advocacy, informs about best practices and communicates discoveries and achievements to partners and target audiences.